More irreproducible chromatin
نویسندگان
چکیده
منابع مشابه
Top Tips to Make Your Research Irreproducible
Software Sustainability Institute, University of Edinburgh, UK Department of Computing & Information Systems, Cardiff Metropolitan University, UK School of Computer Science, University of St Andrews, UK Insight Centre for Data Analytics, University College Cork, Ireland Microsoft Research, Cambridge, UK [email protected] http://www2.epcc.ed.ac.uk/~neilc/ [email protected] http://d...
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Many people believe that a coin in ordinary currency will come up heads nearly half the time it is tossed. Few people have reported a systematic experimental test of that belief. During World War 11 an English statistician. J. E. Kerrich, was in Denmark when the Germans overran it. In te rned under benevolent Danish supervision, he performed and recorded (Kerrich 1946) 10,000 spins of an ordina...
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10.1083/jcb.200801036 Thomson Scientifi c has posted a response ( 1 ) to our editorial on the reliability of their impact factor data ( 2 ). In it, they claim that our interpretation of the communication between our offi ce and their Research Services Group was “ misleading and inaccurate ” . We have already published some excerpts from these communications in our previous editorial. For propri...
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There is no real worry that this is due to scientific misconduct. Rather, it is believed to be due to poor training of investigators in experimental design, lack of reporting of methodologies in published papers, lack of critical evaluation and reviewing, and lack of publications on negative data or on critiquing others’ methods. Other forces such as various kinds of bias presumably contribute ...
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In all eukaryotes, the heterohexameric MCM2-7 complex functions as the main replicative helicase during S phase. During early G1 phase, it is recruited onto chromatin in a sequence of reactions called pre-replication complex (pre-RC) formation or DNA licensing. This process is ATP-dependent and at least two different chromatin-bound ATPase activities are required besides several others essentia...
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ژورنال
عنوان ژورنال: Cell
سال: 1979
ISSN: 0092-8674
DOI: 10.1016/0092-8674(79)90247-2